Cannabis in Molecules: Cannabinol (CBN)
Cannabinol (or CBN) is one of the most prevalent and best studied substance of Cannabis, along with THC and CBD.
In this video you will discover Cannabinol’s multiple uses, from burn management to bone formation and much more.
Subscribe to our Newsletter for a monthly update on all things natural and unique discounts on your favourite eco-conscious products.
Did you like this video?
This original content has been offered for free without advertisements thanks to our readers’ contributions. You, too, can support us in many ways. Check out how here! Thank you
Copyright, Nature Going Smart. May not be re-printed without permission.
References of the studies cited :
Rhee, M. H., Vogel, Z., Barg, J., Bayewitch, M., Levy, R., Hanuš, L., Breur, A. & Mechoulam, R. 1997. Cannabinol Derivatives: Binding to Cannabinoid Receptors and Inhibition of Adenylylcyclase. Journal of Medicinal Chemistry, 40, 3228-3233.
Flaubert, B. L. & Kaminsky, N. E. (2000). AP-1 activity is negatively regulated by cannabinol through inhibition of its protein components, c-fos and c-jun. J Leukoc Biol, 67, 259-66.
Herring, A. C., Faubert Kaplan, B. L. & Kaminsky, N. E. (2001). Modulation of CREB and NF-κB signal transduction by cannabinol in activated thymocytes. Cellular Signalling, 13, 241-250.
Turner CE, Elsohly MA, Boeren EG (1980). Constituents of Cannabis sativa L. XVII. A review of the natural constituents. J Nat Prod 43: 169–234.
Qin N, Neeper MP, Liu Y, Hutchinson TL, Lubin ML, Flores CM (2008). TRPV2 is activated by cannabidiol and mediates CGRP release in cultured rat dorsal root ganglion neurons. J Neurosci 28:
Wilkinson JD, Williamson EM (2007). Cannabinoids inhibit human keratinocyte proliferation through a non-CB1/CB2 mechanism and have a potential therapeutic value in the treatment of psoriasis. J Dermatol Sci 45: 87–92.
Scutt A, Williamson EM (2007). Cannabinoids stimulate fibroblastic colony formation by bone marrow cells indirectly via CB2 receptors. Calcif Tissue Int 80: 50–59.
Holland ML, Allen JD, Arnold JC (2008). Interaction of plant cannabinoids with the multidrug transporter ABCC1 (MRP1). Eur J Pharmacol 591: 128–131.